Fallout 3 / New Vegas version work with both these games the same.
Requirement of the mod to work properly is hdr must be enabled in game video options.
Most versions do not support hardware antialiasing, so do not enable it in game video options or in video driver control panel (especially important for AMD users), overwise you will see bugs (transparent objects is the most common artifact). Deferred rendering do not support antialiasing in dx9 and it used for higher blending quality of ambient occlusions and detailed shadows.
Many software types have compatibility issues with the mod because they hook in to game process or graphics, so make sure you do not run anything like that. This includes Steam overlay, EVGA, Afterburner, Avast antivirus, EMET, D3D Overrider, Razor and Logitek utils.
ENBoost memory manager is included in all versions after 0.202, if you don't need graphic effects, disable the mod in enbseries.ini
Not many effects made, because engine use multipass rendering and 2_0 shaders, this require too much effort to modify manually (parallax for terrain only possible with rewriting shaders to 3_0).
Implemented color and lighting corrections, programmable post processing effects, sun rays, ambient occlusions and indirect lighting, detailed shadows.
Included default preset is not configured, download customized from other sites like Nexus or from the forum.